Recommendations

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Recommendations

Initial Reorientation

Before the actual registration is addressed, the images should be brought into a consistent orientation. If this is not the case after loading, the images may be reoriented. There are shortcut buttons in the lateral taskbar to achieve this conveniently.

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Initial rearrangement of the INP images by mirroring and rotations with the panel
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Reorient the image to Standard orientation HFS

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Similar for the REF images..

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Initial reorientation of the INP images by arbitrary translations and rotations with the reslicing panel.

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Similar for the REF images by arbitrary translations and rotations with the reslicing panel.

In the example below, the reference needs to be straightened. Activate picture_7513, shift the fusion balance fully to REF, and then rotate the axial image.

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Transformation Initialization

The next step is to ensure that the initialization is appropriate. This means that the images are either already aligned on the REFERENCE sub-page, or that they are brought into a reasonable overlap as described above.

Layout Adjustments

Initially the images will appear in orthogonal layout (Ctrl+D) which allows working easily in all 3 dimensions. For fine adjustments it may be preferable to switch to the axial (Ctrl+Z), coronal (Ctrl+Y) or sagittal (Ctrl+X) single-plane layout.

Restriction of Matching Volume

In some cases the automatic matching procedure needs to be restricted to a sub-volume of the data. This can be achieved in different ways.

As described above, the In box option allows defining a box in the reference image, top which the registration algorithm will be confined. An alternative is to define a free-form masking volume on the input or reference image using the selections from the lateral taskbar illustrated below.

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Prepare input mask opens the segmentation tool described in the PMOD Base Functionality Guide for generating a mask file. Mask by file allows selecting an existing mask file

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which can be inspected with the picture_7583 button. Note that each input file has its own mask definition

Registering Dynamic Images to a Reference

In the case of a dynamic INP series it is recommended to proceed as follows:

1.Check whether there is motion in the data. If there is, a motion correction should first be applied.

2.Calculate an average image from some dynamic frames. Typically, early PET frames will result in a perfusion-related image which provides a good pattern for registration to an MR image.

3.Match the average image to the reference.

4.Apply the resulting transformation to the dynamic series, as described above.