List of Implemented Models

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List of Implemented Models

The following lists provides a quick overview of the implemented models. If one of the models does not appear in the Model list of the Menu it may have been hidden and can be added using the configuration facility.

Note that outdated models from previous versions have a "Legacy" in the name. These models are only supported for backward compatibility.

Models with Blood Data

Model Name

Data

Dynamic?

Blood?

Vt (3 Calc Methods)

Tracers without irreversible uptake.

yes

yes

Vt (Logan Plot)

Tracers without irreversible uptake.

yes

yes

Vt (RE-GP Analysis, Zhou)

Tracers without irreversible uptake

yes

yes

1-Tissue (Alpert)

Tracers which allow time-weighted integral solution.

yes

yes

1-Tissue (Zhou GRRSC)

Tracers with 1-tissue compartment kinetics

yes

yes

2-Tissue Compartments, K1/k2

Tracer with 2-tissue compartment kinetics; preferably with K1/k2 constant and k4=0.

yes

yes

2-Tissue K1/k2, RR

Tracer with 2-tissue compartment kinetics. Fit with Ridge-Regression

yes

yes

2-Tissue (BFM)

Tracer with 2-tissue compartment kinetics, particularly suited for FDG. Basis function fit

yes

yes

Multiple Linear Analysis (MLAIR)

Tracer with irreversible trapping.

yes

yes

MBF NH3 (BFM)

Dynamic NH3 PET of the heart. Acquisition duration 4 minutes.

yes

no

Spectral Analysis SAIF

PET data set using a tracer with irreversible trapping

yes

yes

Receptor Reference Models

Model Name

Data

Dynamic?

Blood?

BPnd (6 Calc. Methods)

Reversible receptor tracers

yes

no

BPnd (Ichise MRTM0 Ref)

123I IBF, 11C Raclopride

yes

no

BPnd (Ichise MRTM Ref)

11C DASB

yes

no

BPnd (Ichise MRTM2 Ref)

11C DASB

yes

no

BPnd (Logan Ref)

11C Raclopride, 11C dMP

yes

no

BPnd (SRTM Ref)

11C Raclopride, 11C CH 23390, 11C CTF

yes

no

BPnd (Wu SRTM2 Ref)

11C Raclopride, 11C Flumazenil, 18F FCWAY

yes

no

K (Patlak Ref)

FDOPA or another irreversibly binding tracer with a suitable non-trapping reference

yes

no

Displacement (LSRTM)

PET data set with a baseline part and an activation part

yes

no

MP4A (Nagatsuka RLS Ref)

11C-MP4A, acetylcholine analog

yes

no

Brain Glucose Consumption

Model Name

Data

Dynamic?

Blood?

MRGlu (FDG Patlak)

18FDG-PET

yes

yes

MRGlu (FDG Autorad)

18FDG-PET

yes

yes

C14 Autoradiography

14C labeled glucose, autoradiographic cuts

no

yes

C14 Autoradiography; Glucose variable

14C labeled glucose, autoradiographic cuts

no

yes

Models for Dynamic FDG Whole-body Scans

Model Name

Data

Dynamic?

Blood?

MRGlu (FDG Patlak, Slice-dependent Times)

18FDG-PET acquired with non-stationary scanner field-of-view

yes

yes

MRGlu (FDG BFM, Slice-dependent Times)

18FDG-PET acquired with non-stationary scanner field-of-view

yes

yes

Brain Perfusion and Blood Volume

Model Name

Data

Dynamic?

Blood?

rCBF (Alpert)

H215O-PET

yes

yes

rCBF (Watabe Ref)

H215O-PET

yes

no

rCBF (Autorad)

H215O-PET

no

yes

rBV (Autorad)

11CO-PET

no

yes

Models for MR Data

Model Name

Data

Dynamic?

Blood?

Diffusion Tensor (DTI MIR)

DTI/DWI MRI data

yes

no

Diffusion ADC (DWI MRI)

DWI MRI data without diffusion tensor information

yes

no

Perfusion (pCASL MRI)

Control, label and proton density images as three separate series

yes

no

Resting State (RS fMRI)

Resting state MRI data

yes

no

4D Flow Measures

MR data acquired using a 4D flow acquisition

yes

no

Turbulent Kinetic Energy

MR data acquired using a 4D flow non-symmetric four-point acquisition

yes

no

Miscellaneous Models

Model Name

Data

Dynamic?

Blood?

Correlation

Any dynamic Volume Data

yes

no

Regression

Any dynamic Volume Data

yes

no

Fourier Analysis

Any dynamic Volume Data

yes

no

Fractal Dimension

Any dynamic Volume Data

yes

no