- 1 -

1. Empty Brain Norm Creation

- 2 -

2. Control Samples Addition

- 3 -

3. Normalization Definition and Sample Normalization

3D Rendering of Brain VOIs

- 4 -

4. Calculation of Normal Pattern

- 5 -

5. Variance Definition for z-Score Calculation

- 6 -

6. Comparison Settings

- 7 -

7. Result Mask Specification

IconBatch Mode Brain Norm Deviation
Icon7. Result Mask Specification

- 8 -

8. Brain Norm Saving

- A -

AAL Single-Subject Atlas

AAL-Merged Atlas

AAL-VOIs Atlas

Amyloid Cortical Composite

Anatomical PET Image Loading and PET-PET Matching

Application Notes

Atlas Methodology

Atlas Selection

- B -

Batch Mode

Batch Mode Compare to Norm

Batch Mode Maximum Probability Atlas & Brain Parcellation (Brain VOIs)

Brain Norm Creation

IconPET-based Normalization
IconBrain Norm Creation

Brain Norm Editor

Brain Norm Functionality

Brain Parcellation

Brain Parcellation Implementation in PNEURO

Brain Segments Calculation

IconBrain Segments Calculation
IconBrain Segments Calculation
IconBrain Segments Calculation
IconBrain Segments Calculation

Brain Spill-out (Muller-Gartner)

IconBrain Spill-out (Muller-Gartner)
IconBrain VOI Editing and Statistics Calculation

Brain Structures

Brain VOI Editing and Statistics Calculation

IconBrain VOI Editing and Statistics Calculation
IconBrain VOI Editing and Statistics Calculation
IconBrain VOI Editing and Statistics Calculation
IconBrain VOI Editing and Statistics Calculation
IconBrain VOI Editing and Statistics Calculation
IconBrain VOI Editing and Statistics Calculation
IconStatistics of Dynamic PET Data
Icon6. Comparison Settings

Brain VOI Tools: Common Features

Brain VOIs Based on Maximum Probability Atlas

Brain VOIs Based on T1-MRI Segmentation

- C -

Compare to Norm Patient Data Analysis

Cynomolgus Monkey Atlas

- D -

Data Inspector

Domestic Pig / Minipig Brain Atlas (CH.Malbert)

- E -

Example Database

- F -

Filter

Functional PET Image Loading and Time Averaging

IconFunctional PET Image Loading and Time Averaging
IconPET Image Loading and Time Averaging

- G -

Grey Matter Spill-out and White Matter Spill-in (Muller-Gartner)

IconGrey Matter Spill-out and White Matter Spill-in (Muller-Gartner)
IconBrain VOI Editing and Statistics Calculation

- I -

Image Association

Interpolation

IconInterpolation
IconReduce Matrix

- L -

Landmark Definition and MR Segmentation

Landmark Definition and Parcellation

IconLandmark Definition and Parcellation
IconLandmark Definition and MR Segmentation

LMA Variant of GTM Method

IconLMA Variant of GTM Method
IconBrain VOI Editing and Statistics Calculation

- M -

Mapping of Pixels from Scatter Plots

Maximum Probability Atlas Implementation in PNEURO

Methodology

MR Image Loading and Denoising

MR Image Loading and Segmentation

IconMR Image Loading and Segmentation
IconMR Image Loading and Segmentation
IconMR Image Loading and Segmentation
IconMR Image Loading and Denoising
Icon3. Normalization Definition and Sample Normalization

MR Loading Configuration

MR-based Normalization

IconMR-based Normalization
IconMR-based Normalization

- N -

N30R83 Brain Structures

N30R83 Maximum Probability Atlas

- O -

Outlining of Brain Structures

IconOutlining of Brain Structures
IconOutlining of Brain Structures
IconOutlining of Brain Structures
IconOutlining of Brain Structures
IconOutlining of Brain Structures

- P -

Parametric Mapping

IconBrain VOI Editing and Statistics Calculation
IconParametric Mapping

Parcellation Result and Matching with PET

Parcellation Result and Outlining of Brain Structures

Partial-Volume Correction (PVC)

IconPartial-Volume Correction (PVC)
IconBrain VOI Editing and Statistics Calculation

Peak VOI and Iso-contouring VOI

IconData Inspector
IconPeak VOI and Iso-contouring VOI

PET Image Loading

PET Image Loading and Time Averaging

IconPET Image Loading and Time Averaging
IconPET Image Loading and Time Averaging
IconPET Image Loading and Time Averaging
IconPET Image Loading and Time Averaging

PET to MR Matching

IconPET to MR Matching
IconOutlining of Brain Structures
IconLandmark Definition and Parcellation
IconParcellation Result and Matching with PET
IconLandmark Definition and MR Segmentation

PET-based Normalization

IconPET-based Normalization
IconPET-based Normalization

PMOD Copyright Notice

PMOD Database Functionality

IconBatch Mode Maximum Probability Atlas & Brain Parcellation (Brain VOIs)
IconPMOD Database Functionality

PMOD Neuro Tool Introduction (PNEURO)

PMOD ToolBox

IconPMOD Neuro Tool Introduction (PNEURO)
IconPMOD ToolBox

Protocols

- Q -

Quality Control Capture

Quality Control of Normalization

- R -

Recommendations for Brain VOI Calculations

Reduce Matrix

References

Region-based Voxel-wise (RBV)

IconRegion-based Voxel-wise (RBV)
IconBrain VOI Editing and Statistics Calculation

Replace Values

Run All

- S -

Saving Intermediate Results

Scale Values

Sharing Databases

Statistics of Dynamic PET Data

Statistics of Static Data

Statistics Results

IconBrain VOI Editing and Statistics Calculation
IconBrain VOI Editing and Statistics Calculation
IconBrain VOI Editing and Statistics Calculation
IconBrain VOI Editing and Statistics Calculation
IconBrain VOI Editing and Statistics Calculation
IconStatistics Results

Structure of VOI Atlases in PMOD

- T -

Template-based Normalization

Tree Organization of Atlas VOIs

IconTree Organization of Atlas VOIs
IconDomestic Pig / Minipig Brain Atlas (CH.Malbert)
IconBrain VOI Editing and Statistics Calculation
IconBrain VOI Editing and Statistics Calculation

- U -

User Interface

IconUser Interface
IconBrain VOI Editing and Statistics Calculation
IconBrain VOI Editing and Statistics Calculation

- V -

VOI Analysis

VOI Based Partial-Volume Correction (GTM Method)

IconVOI Based Partial-Volume Correction (GTM Method)
IconRegion-based Voxel-wise (RBV)
IconBrain VOI Editing and Statistics Calculation

- W -

Workflow for Functional and Anatomical PET

Workflow for MR-only Studies

IconWorkflow for MR-only Studies
IconWorkflow for MR-only Studies

Workflow for PET-only Studies

Workflow for Studies with PET and MR

Workflow for Studies with PET and MRI

IconMaximum Probability Atlas Implementation in PNEURO
IconWorkflow for Studies with PET and MRI

- Z -

z-score

Icon5. Variance Definition for z-Score Calculation
Iconz-score

Z-Score Analysis